GBM– tag –
-
Glioblastoma Series | Part 6: Seeing What Matters — Composite Diagnostics (Imaging × Transcriptome × CNV)
Seeing What Matters — Composite Diagnostics (Imaging × Transcriptome × CNV) Therapy moves only when we can answer “for whom, when, and what.” This chapter maps a beginner-friendly framework for composite diagnostics across imaging, trans... -
Glioblastoma Series | Part 5: Plasticity & Escape — A Gentle Guide to OPC/AC/MES State Transitions
Plasticity & Escape — A Gentle Guide to OPC/AC/MES State Transitions Why do single agents rarely suffice? Because GBM has plasticity—it can shift among OPC-like, AC-like, and MES-like faces. Let’s build intuition and turn it into a p... -
Glioblastoma Series | Part 4: The Moving Tumor — Intuitive Guide to ECM, Adhesion, and White-Matter Tract Invasion
The Moving Tumor — Intuitive Guide to ECM, Adhesion, and White-Matter Tract Invasion Why does GBM come back even after “maximal” surgery? This beginner-first chapter explains the mobility of GBM via ECM, adhesion signaling, and the highw... -
Glioblastoma Series | Part 3: Extinguishing the Spark — Microenvironment & Immunity (MIF–CD74 Primer)
Extinguishing the Spark — Microenvironment & Immunity (MIF–CD74 Primer) This beginner-friendly chapter looks beyond the tumor mass to the “place” that makes GBM easier to grow: the microenvironment. We introduce brain immunity, ECM, ... -
Glioblastoma Series | Part 2: Where It Begins — SVZ Hypothesis and Precancerous Cells
Where It Begins — SVZ Hypothesis and Precancerous Cells (pre-CC) Beyond the tumor mass: a beginner’s map of how GBM may arise, diversify, and interact with its “niche”. Today’s Goals (3-Minute Preview) Understand what the SVZ (subventric... -
Glioblastoma Series | Part 1: Clinical Map — Symptoms, Diagnosis, Standard of Care, and the Role of TTF
A gentle, beginner-friendly walkthrough of GBM care from first symptoms to initial therapy and what to consider at recurrence—using clear, minimal jargon. Today’s Goals (3-Minute Preview) Recognize common presenting symptoms that trigger... -
Glioblastoma Series | Part 0: Primer — Brain Basics & a By-the-Numbers View of GBM
A beginner-friendly introduction: understand the brain’s building blocks and a simple, number-based overview of GBM (incidence, prognosis, and quality of life). Series Table of Contents Part 0 | GBM Primer: Brain Basics and By-the-Number...
1