Chronic disease– tag –

Introduction: A Map of Aging × Cancer Is Starting to Emerge In this final article of the Expert Series, we step back to ask: In this final article of the Expert Series, we step back to ask: What you will learn Introduction: A Map of Agin...

Introduction: Why “Young” Models Struggle to Capture “Old” Cancer Throughout this Expert Series we have discussed: Throughout this Expert Series we have discussed: What you will learn Introduction: Why “Young” Models Struggle to Capture ...

Introduction: The Gap Between Aging Biology and Everyday Oncology In earlier parts of this Expert Series, we have explored: In earlier parts of this Expert Series, we have explored: What you will learn Introduction: The Gap Between Aging...

Introduction: Adding Lifestyle and Environment to the Genetics–Aging Framework In previous parts of this Expert Series, we focused primarily on “internal” factors: In previous parts of this Expert Series, we focused primarily on “interna...

Introduction: Questioning the Dogma that “Aging = More Cancer” In previous parts of this Expert Series, we have discussed: In previous parts of this Expert Series, we have discussed: What you will learn Introduction: Questioning the Dogm...

Introduction: Why It Is Hard to Model Aging and Cancer Together In earlier parts of this Expert Series, we have discussed: In earlier parts of this Expert Series, we have discussed: What you will learn Introduction: Why It Is Hard to Mod...

Introduction: Reproductive Aging as a Hub Between Women’s Aging and Cancer In Parts 1–3 of the Expert Series, we discussed: In Parts 1–3 of the Expert Series, we discussed: What you will learn Introduction: Reproductive Aging as a Hub Be...

Introduction: Beyond “Aging → Cancer” to “Cancer → Aging” In the Introductory and earlier Expert Series articles, we mainly focused on the direction: In the Introductory and earlier Expert Series articles, we mainly focused on the direct...

Introduction: Aging Is Not Uniform Across the Body In Part 1 of the Expert Series, we focused on “making aging visible” through epigenetic clocks, single-cell analyses, and image-based metrics. In Part 1 of the Expert Series, we focused ...

Introduction: From the Introductory Series to the Expert Series In the Introductory Series (Parts 1–7), we approached the relationship between aging and cancer from multiple angles—historical, molecular, immunologi In the Introductory Se...

Introduction: Screening Is Not Just “The Earlier, the Better” In Parts 1–5, we explored the relationship between aging and cancer from multiple angles: molecular and genetic mechanisms, immune aging, organ-specif In Parts 1–5, we explore...

Introduction: Deconstructing Risk Factors In Parts 1–4 of this series, we explored aging and cancer from several angles: In Parts 1–4 of this series, we explored aging and cancer from several angles: What you will learn Introduction: Dec...

Introduction: The Triangle of Aging, Cancer, and Immunity In Part 1, we explored why cancer is often described as a “disease of aging” and reviewed the historical and conceptual overlap between the hallmarks of aging and the hallmarks of...

Introduction: Zooming in on the “Inner Structure” of Aging Aging and cancer share the same cellular clock—and the same failure modes. Mapping the molecular bridge between senescence and tumor biology reveals the design blueprint for a ne...

Introduction: Why Revisit “Aging and Cancer” Now? The phrase “cancer is a disease of aging” is something most clinicians and life science professionals have heard countless times. The phrase “cancer is a disease of aging” is something mo...

Lead: Kidneys are prone to hypoxia, fueling AKI-to-CKD progression. A 2025 Science study shows that a hypoxia-induced “tRNA-Asp-GTC-3′tDR” safeguards kidney cells by maintaining autophagic flux through RNA autophagy. This adds a new laye...